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Weight regain of 1% from discontinuation was significantly associated with increased hazards of reinitiation of 2.3% (95% CI, 1.9%-2.8%) for patients with type 2 diabetes and 2.8% (95% CI, 2.4%-3.2%) for patients without type 2 diabetes
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Therefore, the interaction of AFs with such molecular targets might negatively cause molecular abnormalities, which later lead to the development of DM
It upregulates collagen, elastin, and tissue repair genes while suppressing inflammation and promoting DNA repair
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