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these changes were associated with activation of the CDK inhibitor, p21, inhibition of various cyclins (A, D1, and E), and induction of apoptosis (30)

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Such innovations save time in diagnosis and enable precision medicine by tailoring therapies to individual tumor biology

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Treatment begins with a 2.5 mg weekly dose for 4 weeks, intended for initiation only, before up-titration in 2.5 mg increments to a maintenance dose of 5-15 mg weekly, depending on individual response and tolerability

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Leading research shows only 1 in 12 remain on a GLP-1 drug for obesity at three years

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