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The trial also showed that the combination produced dose-dependent, sustained weight loss without concerning additional adverse effects the side effect profile was broadly consistent with what would be expected from each individual agent

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For some, a healthy diet and regular exercise just arent enough to melt away stubborn body fat

REDEFINE-1: adults with obesity, no diabetes Design: 3,417 adults with BMI 30 (or 27 with a comorbidity), without type 2 diabetes, for 68 weeks