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Future Directions While preclinical data are compelling, human trials are needed to validate efficacy and dosing
Intermittent fasting has many of the same benefits of the GLP-1 agonists including weight loss and improved metabolic markers which is logical, as the main effect of GLP-1 agonists is to reduce appetite and increase the feeling of fullness with smaller portion size
A total of 4275 patients with vitamin B12 deficiency were included in the final analysis
2 Other GLP-1 drugs such as Mounjaro, Ozempic, Trulicity, Rybelsus , and Victoza (including a generic version) 3 are approved for the treatment of type 2 diabetes, but not specifically for weight management
Potentially good candidates People without insurance coverage for brand-name semaglutide
Risk of hepatic events associated with use of sodium-glucose cotransporter-2 inhibitors versus glucagon-like peptide-1 receptor agonists, and thiazolidinediones among patients with metabolic dysfunction-associated steatotic liver disease
