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GHK-Cu is a complex formed by the GHK tripeptide and a divalent copper ion (Cu)
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People who take certain medications may also be at risk of vitamin B12 deficiency, including, but not limited to, estrogen, H2 receptor antagonists, PPIs (Proton Pump Inhibitors), Chloramphenicol, and Metformin
While rare, serious concerns include rebound hyperpigmentation (darker spots returning after extended use) and ochronosis (blue-black discoloration from prolonged use)