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Kinetic and biochemical analysis of carrier-mediated efflux of drugs through the blood-brain and blood-cerebrospinal fluid barriers: importance in the drug delivery to the brain

Trulicity (dulaglutide) Trulicity (dulaglutide) is an injectable medication that helps improve blood sugar levels and may support weight loss

It has also been used in clinical research as a surrogate measure for gastric emptying [43]

Despite GLP-1 concentration being higher in the fundus than the antrum, its release ex vivo upon IBMX stimulation increases to the same extent in both the fundus and antrum, suggesting a significant contribution to both portal and gastric GLP-1 (Ribeiro-Parenti et al., 2021)

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Postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor