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There are reports that counterfeit GLP-1 drugs from India, Turkey, China, and other foreign sources have infiltrated the U.S

However, the SUSTAIN six trial evaluated semaglutide, a GLP-1 analog, in patients with type 2 diabetes and high cardiovascular risk and discovered that semaglutide was associated with a higher incidence of diabetic retinopathy complications compared to placebo, with a hazard ratio (HR) of 1.76, particularly in patients with pre-existing DR ( This seemingly controversial impact of GLP-1RAs on DR may be because most trials focused on microvascular and cardiovascular outcomes rather than DR

Some notice improved sleep quality and reduced brain fog the same day

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