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Sleep deprivation increases ghrelin (the hunger hormone), reduces leptin (the satiety hormone), increases insulin resistance, and promotes cortisol-driven visceral fat storage

Although SGLT2 inhibitors, metformin, and other agents are well-documented to modulate multiple RCD pathways, it remains unclear whether their clinical renoprotective efficacy is strictly dependent on the specific cell death modality dominant at different stages of DKD progression

For athletes, they also fit naturally into recovery meals when appetite is moderate but not huge

[6] Common side effects include low blood sugar, nausea, dizziness, abdominal pain, and pain at the site of injection

(2020) 142:e26586