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Diabetes GLP-1s perform better but still leak demand: Diabetes-indicated GLP-1s show higher retention (24% at one year) and face fewer access hurdles due to broader coverage and disease framing, yet 76% of demand remains unmet
The fatty acid conjugation is essential for the once-weekly dosing that makes retatrutide dosing schedules practical
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The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signaling
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