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While research most strongly supports Types I, II, and III for skin and joint health, eggshell membrane collagen has been studied for its potential role in supporting joint comfort during physical activity

Growth Hormon IGF Res 8:3945 Flyvbjerg A, Bennett WF, Rasch R, Kopchick JJ, Scarlett JA (1999) Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy, and urinary albumin excretion in experimental diabetes in mice

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Which method is best for you depends on your need, comfort and who is administering the injection

Pickart estimated lethal dose at approximately 22,500 mg for humans (300-fold above effective doses), with animal LD50 studies in mice showing 8 mg per 25g mouse (320 mg/kg, translating to ~22,400 mg for 154 lb human)