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Novo Nordisk and its rival Eli Lilly have waged a two-horse race to dominate the anti-obesity market, with an eye toward expanding to patients who may feel uncomfortable with using an injectable drug

In Phase 2 clinical trials, retatrutide was administered as a once-weekly subcutaneous injection using a structured dose-escalation schedule to improve gastrointestinal tolerability

Three rules cover roughly 80% of muscle preservation on GLP-1 drugs: eat 1.6 to 2.0 grams of protein per kilogram of bodyweight per day, lift heavy 2 to 3 times per week, and keep weekly weight loss under about 1% of bodyweight

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You essentially need to try the medication out so your provider can see how quickly youre losing weight

The Sun et al