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Clinical nutrition ESPEN, 38, 4349

Consequently, there has been discussion regarding antioxidant interventions aimed at reducing the negative consequences of increased oxidative stress, such as lipid peroxidation, mitochondrial dysfunction, and disturbances in neurogenesis factor synthesis (Picca et al

(48) did not support the existence of this proximal-distal incretin loop in humans as intravenous injection of GIP into humans did not enhance GLP-1 secretion, pointing to the fact that the animal models may differ from humans in essential physiology

"There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop," Dr

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9 There is a need for further longitudinal studies to confirm safety, which may slow adoption in broader patient populations