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ISSN 2542-4548
Fasting window: The oral form requires a strict pre-dose fasting period
Doses above 600 mg did not show proportionally greater effects and may increase the risk of gastrointestinal side effects
It supports detoxification, immune balance, oxidative stress reduction, and cellular defense mechanisms throughout the body
The Mn ions further enhance this innate immune signaling by promoting cytosolic DNA sensing, leading to reshaping of the TME toward a more immune-responsive state and robust antitumor immunity in osteosarcoma models (21)
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