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Together, these findings suggest that microbiome shifts associated with trauma exposure and geography may influence PTSD risk by modulating brain structure and neuroinflammatory signaling
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Grape seed procyanidin activates peroxisome proliferator-activated receptor (PPAR), thereby downregulating the expression of cyclooxygenase 2 (COX-2), achieving the regulation of lipid metabolism, inhibiting cell proliferation, blocking the inflammatory cascade, alleviating vascular inflammation, and reversing the vascular structural remodeling of PASMCs (Liu et al., 2020)
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Iprodione and/or chlorpyrifos exposure induced testicular toxicity in adult rats by suppression of steroidogenic genes and SIRT1/TERT/PGC-1alpha pathway
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