The headline number from Lillys announcement of 21 May 2026 was 28.3 per cent average weight loss on 12 mg at 80 weeks around 70 lbs
muciniphila colonization [108]
We also provide Smallest Detectable Differences (SDD) to support interpretation at the individual level
Link Singh, G., Krauthamer, M., & Bjalme-Evans, M
Clear, visible improvement usually takes 812 weeks
Wegovy is FDA-approved for weight management in people with a BMI (body mass index) of 30 or higher or 27 or higher if they have at least one weight-related medical condition, such as: High blood pressure ( hypertension ) Type 2 diabetes High cholesterol Sleep apnea Ozempic is FDA-approved for type 2 diabetes, but since it also contains semaglutide, its often prescribed off-label to help support weight management