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10.1038/ng.686 92 StevensC
Semaglutide is a GLP-1 receptor agonist that mimics the incretin hormone your body naturally produces after eating
Its short half-life of approximately 30 minutes produces discrete, physiological GH pulses rather than the sustained tonic elevation associated with DAC-bound variants
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Pulmonary Aspiration During General Anesthesia or Deep Sedation: Foundayo causes a delay in gastric emptying
The trial also showed that GI side effects were "mostly mild to moderate in severity" and were "partially mitigated with a lower starting dose." This means that many of the side effects people try to manage through timing can also be addressed through dose adjustment
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