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Research from pharmaceutical stability studies confirms this mechanism

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1,2 Although the clinical trials of amitriptyline are old and involved small numbers of patients, a systematic review revealed that amitriptyline tended to show superiority over duloxetine, pregabalin, and milnacipran

Tao, X., West, A

Safety notes: Per the FDA prescribing label, nausea affects 40% of users vs

Concentration affects stability