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Both are powerful brightening agents, but they target dullness, uneven skin tone, dark spots, and acne marks in distinct ways

67,68 Specifically, female sex hormones including estradiol (e.g., 17-oestradiol) 69 protect female proopiomelanocortin (POMC) neurons from IR by enhancing POMC neuronal excitability and coupling insulin receptors to transient receptor potential (TRPC) channel activation

M., Biancur, D

Tsunekawa T, Hayashi T, Suzuki Y, Matsui-Hirai H, Kano H, Fukatsu A et al

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Its known as a growth factor and is part of a group of tissue- and cell-building hormones