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Cost-effectiveness analysis A 2025 cost-effectiveness study published in PubMed found that tirzepatide was dominant over liraglutide from a UK healthcare perspective, meaning it produced both better outcomes and lower costs

Subgroup analyses showed no significant interactions for the six-composite end point across 12 prespecified clinical and demographic subgroups except for a marginal interaction for BMI subgroups

doi: 10.1007/s12035-016-0293-5

Steinbacher, P., & Eckl, P

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These can include: Megaloblastic anemia Leukopenia Neutropenia Pancytopenia in severe cases These extra problems can make things more complicated