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They serve as key signaling molecules in the microbiota-gut-brain axis, directly influencing the central nervous system by crossing the BBB and indirectly modulating neurophysiological processes through immunoregulatory, endocrine, vagus nerve-mediated, and circulatory pathways
Besides the GLP-1R-ROCK-p-MLC signaling pathway, the PI3K-Akt-eNOS-NO-cGMP pathway has also been vital in retinal capillary tone and microvascular patency
doi: 10.1155/2021/1394486 71 GaoHWuH
Corneal confocal microscopy predicts the development of diabetic neuropathy: a longitudinal diagnostic multinational consortium study
Am J Physiol Endocrinol Metab 2017;313:E651-62.ArticlePubMedPMC 100
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