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Topical calcineurin inhibitors are regarded as safe for short-term or intermittent long-term use, although they are generally less effective than corticosteroids

Results accelerated over time At month 1, both treatment groups showed modest gains (10.5 and 11.3 hairs) while placebo declined (-3.6)

Fat tissue converts testosterone to estrogen through an enzyme called aromatase

However, nearly all data come from lab and animal studies rather than controlled human trials, so claims about systemic hormone changes warrant caution

But those upfront costs may be offset by reduced bulk storage requirements, simplified hazardous waste handling, and a decreased reliance on frequent solvent deliveries