24 The oxidative stress and the increase of IOP also causes upregulation of ubiquitin (Ub) and stimulation of the Ub-proteasome pathway: 8, 25 this possibly derives from the activation of the apoptotic program
Verrina, E., Caruso, U., Calevo, M
Un meta-anlisis de 19 estudios prospectivos encontr que las concentraciones ms altas de TMAO en sangre se asociaron con un 62% ms de riesgo de MACE o muerte en comparacin con concentraciones ms bajas (116)

Abbreviations IBD: Inflammatory bowel disease GI: Gastrointestinal CD: Crohns disease UC: Ulcerative colitis T2D: Type 2 diabetes CVD: Cardiovascular disease GLP-1 RA: Glucagon-like peptide 1 receptor agonists CVOT: Cardiovascular outcome trial HF: Heart failure NAFLD: Nonalcoholic fatty liver disease HCC: Hepatocellular carcinoma EEC: Enteroendocrine cell GIP: Glucose-dependent insulinotropic polypeptide TNF: Tumor necrosis factor IL: Interleukin JAK: Janus kinase CCL: C-C motif ligand TGF: Tumor growth factor EGF: Epidermal growth factor KGF: Keratinocyte growth factor HGF: Hepatocyte growth factor cAMP: Cyclic adenosine monophosphate NF-kB: Nuclear factor-kB TCA: T cell activation gene SDF: Stromal cellderived factor M-CSF: Macrophage colony stimulating factor CSMC: Colon smooth muscle cell SSM: Stabilized phospholipid micelles DDS: Dextran sodium sulfate DRA: Downregulated in adenoma BLG: Ban-Lan-Gen ACE: Angiotensin-converting enzyme GPBAR: G proteincoupled bile acid receptor iNKT: Invariant natural killer T cells DPP-4: Dipeptidyl peptidase-4 GLP1/2-Fc: GLP1/2-Fc fusion SCID: Severe combined immunodeficiency disease Ex-4: Exendin-4 IRR: Incidence rate ratio BMI: Body mass index APN: Adiponectin MAT: Mesenteric adipose tissue HFD: High-fat diet TLR: Toll-like receptor NASH: Nonalcoholic steatohepatitis HDL: High-density lipoprotein LDL: Low-density lipoprotein CRP: C-reactive protein PPI: Proton pump inhibitor References Papers of particular interest, published recently, have been highlighted as: Of importance Of major importance Satsangi J, Silverberg MS, Vermeire S, Colombel JF

Comprehensive assessment of sex hormones in Takotsubo syndrome
& Chan, T