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Regulation of the inflammatory response is necessary for limiting tissue destruction and preventing autoimmunity

Vitamin B12 is a water-soluble vitamin, meaning the body excretes any excess through urine rather than storing it

FDA updates are ongoing and do not imply approval or safety

Foundational Discovery Selective Senolytic Elimination in Aged Mice (Cell, 2017 Baar et al.) FOXO4-DRI Restores Fitness, Fur Density, Renal and Liver Function in Aged Mice The foundational study introducing FOXO4-DRI as a senolytic peptide was published in Cell by Baar and colleagues in 2017

Reduction in senescent cell concentration, which otherwise contribute to inflammation and tissue damage

New England Journal of Medicine , 390(8), 712-724