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In a model of non-ischemic HF in dogs (tachycardiomyopathy induced by pacemakers), IV infusion of GLP-1 increases left ventricular (LV) contractility (LV dP/dt increased by 98%, stroke volume by 102%, and cardiac output by 57%) and decreases LV end-diastolic pressure, heart rate, and systemic vascular resistance

Activation of osteoblast ferroptosis via the METTL3/ASK1-p38 signaling pathway in high glucose and high fat (HGHF)-induced diabetic bone loss

doi: 10.1007/s10585-015-9732-3 119 OlubamiwaAOLiaoT-JZhaoJDehannePNobanCAnginYet al

Activation of microglia and iron accumulation in APP/PS1 mice has been associated with neuroinflammation and A aggregation (McIntosh et al., 2019)

doi: 10.1210/clinem/dgaa891 50 AlanteetAAAttiaHAShaheenSAlfayezMAlshanawaniB