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Research suggests MOTS-c may support metabolism by influencing glucose handling, insulin sensitivity, and how cells use fuel

They also undermine the medications blood sugar benefit

The tolerability of GLP-1 drugs can also pose a challenge, as gastrointestinal issues like nausea, vomiting, diarrhea and constipation can occur from taking them

Focus on nutrient-rich, whole foods

Butyrate serves as a primary energy source for colonocytes and enhances intestinal barrier integrity by increasing the expression of tight junction proteins like occludin, which is vital for preventing systemic inflammation 34

So when is obesity a chronic recurring disease, and what are the implications of now being able to use that label