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Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats

The most common side effects were also gastrointestinal and neurological in nature

Zepbound is also the only FDA-approved prescription medicine for moderate-to-severe obstructive sleep apnea in adults with obesity

The peer-reviewed findings will be presented on Saturday (June 13) at ENDO 2026, the Endocrine Societys annual meeting

Certain factors may increase susceptibility to burping and related gastrointestinal symptoms, including: Rapid dose escalation (not following the recommended titration schedule) Concurrent use of other medications affecting gut motility (such as opioids or anticholinergics) Pre-existing gastrointestinal conditions such as gastroparesis or gastroesophageal reflux disease (GERD) Dietary habits that promote gas production Gastrointestinal adverse effects, including burping, are generally more common and pronounced at higher doses, which explains the higher rates observed with Wegovy compared to Ozempic