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Across the SURPASS program, weight loss associated with tirzepatide explained the majority of treatment effect on SBP

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A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus

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Antagonism of rat beta-cell voltage-dependent k+ currents by exendin 4 requires dual activation of the cAMP/protein kinase a and phosphatidylinositol 3-kinase signaling pathways

Following US Food and Drug Administration approvals, GLP-1 (glucagon-like peptide-1) receptor agonists such as type 2 diabetes drug semaglutide have revolutionised the international weight-loss industry by suddenly offering surprisingly effective obesity treatments