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Even in binge eating disorder, appetite reduction may not address the emotional roots of the condition

As growth hormone signaling increases, downstream effects, such as changes in fluid balance, sleep patterns, and tissue repair, can temporarily create side effects during early use

But losing more than 1.5%2% of body weight per week raises the risk of muscle and bone loss

Twice-weekly protocols (0.51ml every 34 days) are appropriate during active weight loss phases or when treating hepatic steatosis but are not necessary for maintenance

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