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The effects of Glu are mediated by ionotropic glutamate receptors (iGluRs), ligand-gated ion channels which are categorized into four distinct subclasses based on their selective agonists: -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs), kainate receptors (KARs), N -methyl-D-aspartic acid receptors (NMDARs), and receptors (GluDs) (Hansen et al., 2021) (Figure 1A)

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doi: 10.1080/15548627.2021.1938914 36 JiRZhangZYangZChenXYinTYangJ

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