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Post-trial follow-up data from EMPA-KIDNEY suggest that cardiorenal benefits may persisted for up to 1 year after treatment cessation, highlighting the importance of continued therapy for long-term effectiveness [117]

Sublingual administration achieves 55% penetration after 10 minutes and approximately 70% after 30 minutes through oral epithelium

Also, talk about whether a lower dose or a slower weight loss journey would be safer for avoiding side effects

Garg R, et al

Target-mediated pharmacokinetic/pharmacodynamic model based meta-analysis and dosing regimen optimization of a long-acting release formulation of exenatide in patients with type 2 diabetes mellitus

In contrast, obesity is assessed using imprecise metrics like body mass index, lacks standardized treatment goals, and is often misunderstood as a lifestyle issue rather than a chronic, relapsing disease