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J Natl Cancer Inst 82: 107112

In rodent models, semaglutide reduces food intake and body weight

Studies on metabolic rate after GLP-1 medication discontinuation show that resting metabolic rate returns to predicted levels based on new body weight within 3-6 months

This followed new provisions included in the Food and Drug Omnibus Reform Act of 2022, which gave the FDA authority to improve transparency around accelerated approvals and ensure that applicants complied with post-marketing requirements

None of it did much good unless the patient didnt have enough B12 based on a blood test

When you lose fluids through GI side effects, you also lose electrolytes