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Side effects tend to get worse or appear after dose changes as your body needs time to adjust to the higher level of medication
This is of particular concern given the European Medicines Agencys (EMA) recent alert regarding a possible link between GLP-1 receptor agonists and an increased risk of suicidal ideation and behavior (10, 11)
But there is still a lot about these treatments that are unknown
In high-fat-fed rats, [dA(2)]GLP-1/GcG reduced body weight nonfasting plasma glucose, and boosted circulating plasma insulin concentrations when given twice daily for 21 days
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Seek medical advice if you experience severe or worsening cognitive impairment affecting daily functioning, sudden confusion, symptoms suggestive of hypoglycaemia, signs of severe dehydration, accompanying neurological symptoms (severe headache, visual disturbances, weakness), significant mood changes, or persistent symptoms not improving with supportive measures after 24 weeks
