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These include: Vitamin C: Besides its anti-inflammatory properties, vitamin C is a well-known immune booster

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In a randomized, double-blind, placebo-controlled trial in 2,919 participants (65 years) with elevated blood concentrations of homocysteine, supplementation with vitamin B 12 (500 g/day) and folic acid (400 g/day) for two years did not decrease the risk of osteoporotic fracture despite reductions in homocysteine (120, 121)

Moreover, Largo, et al showed that treatment with GS suppressed IL-1-induced COX-2 expression through transcriptional downregulation and suppression of NF-B DNA binding activity in human chondrocytes 22 , and as well, decreased COX-2 expression on peripheral blood mononuclear cells in rabbits with atherosclerosis aggravated by chronic arthritis 32

ROS generated during aluminum stress formed toxic aldehydes in reaction with fatty acids and caused severe root growth inhibition

Pediatr Nephrol 23:863878