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Since then, several clinical studies have shown its safe and effective use - but the pharmacuetical companies have decided not to (yet) pursue FDA-Approval (likely because each new FDA-Approval costs several million dollars to go through the process, and because there are a good deal of drugs used off-label in the way tranexamic acid is for melasma, especially when the drug has a long history of safety and efficacy, as is in this case)
investigational only
Expert Rev Vaccines
doi: 10.1210/jc.2010-0490
However, it would be easier to identify and record the number of hospitalizations, intensive care unit visits, and fatalities during vaccine trials when compared to infections, thus making it more feasible to assess the efficacy of a vaccine against severe disease
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