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Phillips E, Shear N
So can chemical signals that act on melanocortin receptors in the skin
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In SURMOUNT-1, the most common treatment-emergent adverse events were gastrointestinal: nausea (24.6-33.3% across doses vs 9.5% placebo), diarrhea (18.7-21.2%), vomiting (5.7-12.2%), and constipation (5.8-11.5%)
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Lixisenatide is a 44 amino acid synthetic peptide derivative of exendin-4 [ Figure 2 , Table 1 ]
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