We are conscious of the limitations of the animal models [123], however in a clinical trial undertaken by this group to asses IGF-1 in liver function under cirrhosis with these same dosage (20 g/kg/day) no side effects were reported and liver function greatly increased [108]
Serious side effects are uncommon when sermorelin is prescribed at appropriate doses under medical supervision with regular IGF-1 monitoring
Research models have also documented GHRP-2's potential involvement in ghrelin-associated orexigenic and metabolic signaling pathways in preclinical models
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