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The opposite pattern, losing limb circumference while waist remains stable, suggests muscle loss that requires intervention

The headline result was a mean 17.5% body-weight reduction at 24 weeks in the 12 mg arm, with clear dose-response behavior across the four active doses

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This inability to induce hypoglycemia, or low blood sugar levels, in IV-administered GLP-1 led to the development of GLP-1 receptor agonists

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