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In research published in the journal Diabetes, Obesity and Metabolism on nearly 2,000 adults with obesity, participants took weekly semaglutide injections in addition to making healthy lifestyle changes for 68 weeks, then stopped
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Researchers who have plateaued on dual agonists are exploring whether the switch from tirzepatide to retatrutide provides another level of receptor novelty and metabolic activation
While their mechanisms may differ, their combination has been proposed to provide complementary or synergistic actions
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