In terms of safety, the main adverse event of RFA is esophageal stricture, with an incidence of approximately 5% reported in the meta-analysis and 11.8% reported in the SURF trial, but this can usually be resolved through endoscopic dilation
For example, on average 63% of excess choline, and 31% of carnitine (+-13%) are converted to TMA [20] by an average gut profile - even if dysbiosis raised these values to 100%, it would still not meet the thresholds as above for precursor overload on a regular diet
Contact your trial team promptly, as they are responsible for assessing and reporting adverse events for investigational medicines
Elevated serum B12 levels may sometimes indicate underlying medical conditions rather than true overdose, warranting clinical investigation to exclude haematological disorders, liver disease, or renal impairment
It is designed for convenient daily use at home while still supporting the bodys glutathione levels
If results plateau or side effects interfere with life, we adjust