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The results showed a 20% reduction in the risk of a composite of cardiovascular death, nonfatal myocardial infarction (MI) or nonfatal stroke relative to placebo over approximately 40 months of follow-up

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[PMID: 25874752] PubMed record related to this compound for laboratory literature review

Unlike other GH secretagogues, ipamorelin very surprisingly does not induce a significant increase in adrenocorticotropic hormone (ACTH) or cortisol levels

[21] [22] Conversely, symptoms of adrenal insufficiency such as severe fatigue, weight loss, hypotension, or hypoglycemia require urgent assessment, typically starting with morning serum cortisol and possibly ACTH stimulation testing

Decongestants containing pseudoephedrine or phenylephrine have additive sympathomimetic effects with stimulants, raising the risk of hypertension, tachycardia, and anxiety