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Consistently, by ChIP assay, we detected significant NRF2 binding in Nqo1 and Slc7a11 loci, along with induced association of H3K4Me4 and H3K9Ac after DMF treatment (Fig

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GI adverse events were most common, including nausea (17.3% vs 16.1% vs 14.2%, respectively), diarrhea (11.6% vs 12.0% vs 7.7%, respectively), and vomiting (10.1% vs 9.1% vs 6.4%, respectively)

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