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AS SKIN WHITENING Glutathione competes with the receptor that causes Tyrosinase activity thus inhibiting it

Moreover, metformin stimulates GLP-1R and PKA signalling via AMPK-dependent pathway, which may account for its synergistic protective effects with liraglutide

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As another isogenic pair, we used an euploid ESC line KhES1 and trisomy KhES1 subclone with chromosome 21 artificially introduced 36,53

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