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Notably, GSH binding motif is not conserved among the other seleno-GPxs (GPx2, GPx3, GPx4, and GPx6) justifying their abilities to use wide variety of thiols like cysteine, protein thiols, mercaptoethanol, and dithiothreitol in addition to GSH as reducing equivalent for the catalysis [8, 17, 18]
The consistency is not thick
Retinol + Vitamin C Retinol + Vitamin C Retinol and Vitamin C work best at different pH levels, and using both at the same time may destabilize each other and reduce effectiveness