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Increased risk of cardiovascular diseases Since cardiovascular disease is a leading cause of death in women, monitoring B12 levels is essential, particularly for women with a family history of heart disease or other risk factors like obesity and hypertension

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Reynolds et al., 2021)

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In the context of our findings, the proposed signaling involvement (NF-B, MAPK, MLCK, Nrf2, and Akt/FOXO) represents plausible mechanistic interpretations consistent with previous reports, rather than pathways directly quantified in the current experiment 18,21,29,31,32

Enzymatic and Chemical Synthesis for ADP-Ribosylation Using NAD(+) as Building Blocks: New Concerns in Reaction Discovery and Design