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Enzymes that function primarily in the reductive direction utilize the NADP + /NADPH co-factor pair as their co-factors as opposed to oxidative enzymes that utilize the NAD + /NADH co-factor pair
SLC25A20 can inhibit both in vitro and in vivo growth and metastasis of HCC by suppressing the G1S cell cycle transition and epithelialmesenchymal transition and inducing apoptosis [17]
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Mol Cancer Ther
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