No, you should never freeze a reconstituted peptide like Retatrutide
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Intranasal delivery has been investigated for peptides such as albumin, exendin/GLP-1, GALP, insulin, leptin, and PACAP, with studies indicating that it can achieve rapid brain exposure while minimizing systemic side effects
Brown JM, Hazen SL
[PMID: 19733091] PubMed record related to this compound for laboratory literature review