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An agonist activates a receptor

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Accordingly, incretin-based therapies, such as DPP-4 inhibitors and GLP-1 receptor agonists (GLP-1 RAs) that are resistant to degradation by DPP-4, have been introduced in the market within the past decade to overcome and extend the short half-life of the incretin effect

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Most GLP-1 users (63%) say theyre using the drug for diabetes management, while 47% are using it for weight loss14% are using it for both diabetes and weight loss