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[10] Long-term supplementation with relatively large amounts of folic acid is associated with a small reduction in the risk of stroke [11] and, for "relatively large amount" meaning 400 g/day, an increased risk of prostate cancer

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We hope that our work will bring more attention to how organelles and their metabolites are relevant to cancer biology, says Kivan Birsoy, head of the Laboratory of Metabolic Regulation and Genetics at Rockefeller