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For example, an LCKD (low-carbohydrate, ketogenic diet) is an effective method for losing weight, improvement of fasting insulin as well as free testosterone levels in obese and overweight women with PCOS

For women, E 2( t ), varies from 0.135 to 1.156 nM over the course of the cycle [24,25] , and for men, E2 is a constant 0.09 nM [26]

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The study reported changes in model-system outcomes under experimental conditions, but these findings remain limited to preclinical research and should not be interpreted as clinical conclusions