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As the administration volume will be much higher for humans (1.25 mL) than rats (0.5 mL), modeling shows an extension of the pharmacokinetics to maintain therapeutically relevant serum concentrations of drug for 120 days as a larger hydrogel depot will take longer to erode by dissolution (Table S8)
caution in methylation disorders (use only under supervision) No known drug interactions with oral medications, but B12 may mask B9 (folate) deficiencycombined B-vitamin status should be assessed periodically
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Die Injektion von L-Carn 1 g ist bei den oben erwhnten Anwendungsgebieten nur dann angezeigt, wenn eine orale Einnahme von Levocarnitin (z.B
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